Fork tender with bold flavors, this keto Mississippi pot roast recipe combines meaty chuck roast with spicy pepperoncini peppers, beef broth and homemade ranch seasoning. It's a healthier version of the famed Mississippi roast recipe that requires just a few simple ingredients. Serve up tender shreds of Mississippi pot roast on a fluffy bed of mashed cauliflower or cauli rice for an easy meal that the whole family will enjoy!

The original recipe for Mississippi pot roast typically calls for just five ingredients: chuck roast, au jus gravy mix, ranch dressing mix, a whole stick of butter and pepperoncinis.
All of it goes on top of the roast, then it slow cooks in the oven for several hours until it transforms into buttery-soft, melt-in-your-mouth beef roast with maximum flavor.
While this healthier version requires just a few additional ingredients, it's a keto recipe that is still so good and so easy, it will quickly become a family favorite.
why this recipe works
Pot roast is slow cooking at its finest. Similar to my keto pot roast and gravy recipe, this keto Mississippi pot roast cooks low and slow in a Dutch oven, a method that is guaranteed to give you the best roast ever.
Instead of the convenience of a ranch seasoning packet and au jus gravy mix, I'm opting for whole food ingredients (and fewer preservatives) to make this a healthier, low-carb and gluten-free Mississippi pot roast recipe.
It is:
- incredibly tender and flavorful comfort food
- low-carb, gluten free and keto diet friendly
- versatile- enjoy it as a main course with cauliflower mash or shred the beef to use for a variety of meals!
the ingredient list
For the best results, use chuck roast. It is a fatty, tougher cut of beef that becomes melt-in-your-mouth tender when slow-cooked. Chuck roast has amazing flavor and is by far my favorite type of beef to use for pot roast.
This keto Mississippi pot roast recipe is also very versatile. I usually don't add much more than the ranch mix, beef broth, butter and pepperoncinis, but feel free to include other veggies to the Dutch oven. Similar to your traditional pot roast, onion wedges, carrots, and whole garlic cloves will work well.
To make low-carb Mississippi pot roast, you will need:
- chuck roast
- olive oil
- beef bone broth
- pepperoncini brine (from a jar of pepperoncinis)
- onion powder
- garlic powder
- dried dill
- fine sea salt
- ground black pepper
- dried tarragon or chives (optional)
- butter
- sliced pepperoncinis (or 3-4 whole peppers)
The dried herbs and spices are for the homemade seasoning. It takes just a couple of minutes to make and is just as flavorful (and better for you) than a packet of ranch seasoning mix. However, if you already have a ranch mix that you use and love, feel free to substitute it for the spices and herbs.
a keto Mississippi pot roast recipe (Dutch oven)
I love cooking pot roast in a Dutch oven. The cast iron holds and distributes heat really evenly and overall, it will give you better results than a Crock pot or Instant pot pressure cooker.
While those cooking methods can certainly be convenient, my go-to will always be a Dutch oven. 🙂
And since the meat is best when it's seared before slow-cooked, this keto Mississippi pot roast recipe is a one-pot meal! Sear it and slow-cook it in your Dutch oven and you're good to go.
Here's a brief look at the recipe for making Dutch oven Mississippi pot roast. To view the full process, check out the recipe card at the bottom of the page.
Heat the Dutch oven on the stovetop and add the oil. Season the roast with salt and pepper, then sear all sides of the meat until browned. Set the meat on a plate.
Deglaze the pot with the bone broth and pepperoncini brine. Add the pot roast back in and sprinkle the seasoning mix on top. Add the pepperoncinis and butter.
Cover with the lid and transfer to the oven. Roast for 4-5 hours at 275°F, or until tender.
for slow cooker Mississippi pot roast
Mississippi pot roast is a popular slow cooker recipe and you can certainly prepare this low carb version in the Crockpot, too!
Instructions for Crockpot Mississippi pot roast:
- Use a large cast iron skillet to sear the meat.
- Deglaze the pan with the broth and pepperoncini brine, then transfer the juices to the Crockpot.
- Add the meat and the rest of the ingredients. Cook on low heat for 8-10 hours or at high heat for 4-5 hours or until the roast is tender.
recipe tips for the best results
- The cooking time will vary based on the size of the roast. A three-pound chuck roast is usually fork tender after 4 hours.
- Pepperoncini peppers have a mild heat to them and this dish is mildly spicy. You can reduce the amount of heat by using banana peppers and banana pepper brine instead of pepperoncinis.
- Store leftover Mississippi roast in an airtight container for up to 3-4 days. The flavors (and spiciness) will be more intense the next day.
- Use sliced pepperoncinis or whole pepperoncinis if desired. You'll only need 3-4 whole peppers.
what to serve with Mississippi pot roast
Serve this keto Mississippi pot roast with your favorite low-carb sides like cauliflower rice or mash to create a hearty meal (and with few net carbs, it's the perfect keto dinner)!
It's also pretty tasty with low-carb cornbread or keto "buttermilk" biscuits on the side.
The great thing about this fork-tender roast is that you can also turn leftovers into shredded beef to use in a lettuce wrap, tacos, casseroles, soups, stir fry and more.
Savory and mildly spicy with a little bit of pepperoncini tanginess, this Dutch oven Mississippi pot roast recipe features the same bold flavors as the original recipe, but with healthier swaps you can feel good about.
And the best thing about pot roast (of any kind)? It magically tastes even better on a weekend evening, surrounded by my favorite people at the dinner table.
you might also love...
- Brussels sprouts hash makes a lovely side or hearty breakfast topped with eggs! This versatile dish features a delicious medley of salty bacon, tender sweet potatoes and Brussels sprouts.
- Keto chicken fajitas are a weeknight dinner go-to! This easy, under-30-minute meal uses a homemade fajita seasoning mix that is low-carb and gluten-free.
- This low-carb spaghetti sauce recipe creates the most flavorful and meaty spaghetti sauce with allll the aromatics and zero added sugar.
Keto Mississippi Pot Roast
Melt-in-your-mouth tender and packed with flavor, this keto Mississippi pot roast is a healthier, low-carb and gluten-free version of the famed original recipe.
Chuck roast, pepperoncinis, homemade ranch seasoning and butter create the most flavorful pot roast ever!
Ingredients
- 1, 3-pound chuck roast
- 2 tablespoons extra virgin olive oil
- 1 teaspoon sea salt, divided
- 1 teaspoon ground black pepper, divided
- ½ cup beef bone broth
- ½ cup pepperoncini brine (from a jar of pepperoncinis)
- ½ cup sliced pepperoncinis (or 3-4 whole pepperoncinis)
- 1 teaspoon onion powder
- 1 teaspoon garlic powder
- ½ teaspoon dried tarragon or chives (optional)
- ¼ cup butter, sliced
Instructions
- Preheat the oven to 275°F.
- Pour the oil into a large Dutch oven and heat on the stovetop over medium-high heat for 1-2 minutes.
- Season the chuck roast with about ½ teaspoon of salt and ½ teaspoon pepper (set aside remaining ½ teaspoon of each).
- Place the chuck roast into the Dutch oven and sear each side for 3-4 minutes or until browned. Transfer the roast to a plate and turn off the burner.
- Pour the bone broth and pepperoncini brine into the Dutch oven to deglaze the pot, scraping up any browned bits on the bottom. Place the pot roast back into the Dutch oven.
- In a small dish, combine the remaining salt and pepper, onion powder, garlic powder and dried tarragon/chives. Mix well, then sprinkle all of the seasoning on top of the chuck roast (use all of it).
- Add the pepperoncinis on top of the roast and place the butter pieces on top.
- Cover the Dutch oven with the lid and transfer to the oven. Roast for 4-5 hours or until tender.
Notes
- The cooking time will vary based on the size of the roast. Check the roast after 4 hours. I usually cook it for 4-½ hours.
- Pepperoncini peppers have a mild heat to them and this dish is mildly spicy. You can reduce the heat by substituting banana peppers and banana pepper brine instead of pepperoncinis.
- Store leftover Mississippi roast in an airtight container for up to 3-4 days. The flavors (and spiciness) will be more intense the next day.
For Crockpot Mississippi pot roast:
- Use a large cast iron skillet to sear the meat.
- Deglaze the pan with the broth and pepperoncini brine, then transfer the juices to the Crockpot.
- Add the meat and the rest of the ingredients. Cook on low heat for 8-10 hours or at high heat for 4-5 hours or until the roast is tender.
Nutrition Information:
Yield: 8 Serving Size: 1Amount Per Serving: Calories: 531Total Fat: 38gSaturated Fat: 16gTrans Fat: 2gUnsaturated Fat: 19gCholesterol: 169mgSodium: 707mgCarbohydrates: 2gNet Carbohydrates: 2gFiber: 0gSugar: 1gProtein: 47g
This nutritional information is approximate and is provided for convenience as a courtesy.
Did you make this recipe? Let me know!